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Erythrocytosis is a condition in which the body has too many red blood cells, making the blood more concentrated and sometimes thicker than usual. The most frequent example is Polycythemia Vera (PV), a type of blood cancer where the bone marrow produces red blood cells independently of the body’s actual need. High erythropoietin levels often indicate secondary erythrocytosis, while low levels may prompt further testing for primary erythrocytosis. Primary erythrocytosis often results from genetic mutations affecting red blood cell production, with the JAK2 mutation found in approximately 95% of polycythemia vera cases.
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